To create a multiple column layout in LaTeX is easy. What you need is the multicol package.
\usepackage{multicol}
For example, to create a two column layout.
\begin{multicols}{2}
put the contents here
\end{multicols}
To manually break the column, use the
\columnbreak
command.
\begin{multicols}{2}
Column 1 \columnbreak Column 2
\end{multicols}
If you are using standard LaTeX class, such as "article", you can simple create a two column layout using the code below:
\documentclass[twocolumn]{article}